The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 06, 1997
Filed:
May. 17, 1995
Applicant:
Inventors:
Joffre Baker, El Granada, CA (US);
Kenneth Chien, La Jolla, CA (US);
Kathleen King, Pacifica, CA (US);
Diane Pennica, Burlingame, CA (US);
William Wood, San Mateo, CA (US);
Assignees:
Genentech, Inc., , US;
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ;
U.S. Cl.
CPC ...
435331 ; 435 7021 ; 4351721 ; 435 696 ; 43525233 ; 435332 ; 435336 ; 5303879 ; 53038823 ; 5303873 ; 5303913 ; 4241391 ; 4241451 ;
Abstract
Isolated CHF (also referred to cardiac hypertrophy factor or cardiotrophin-1), isolated DNA encoding CHF, hybridomas and cell lines producing antibodies to CHF, and recombinant or synthetic methods of preparing CHF are disclosed. These CHF molecules are shown to influence hypertrophic activity and neurological activity. Accordingly, these compounds or their antagonists may be used for treatment of heart failure, arrhythmic disorders, inotropic disorders, and neurological disorders.