The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 29, 1997
Filed:
Aug. 07, 1995
Applicant:
Inventors:
Hans-Gottfried Genieser, Lemwerder-Ochtum, DE;
Ulrich Walter, Veitshochheim, DE;
Elke Butt, Heissenbuttel, DE;
Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H / ;
U.S. Cl.
CPC ...
536 2612 ;
Abstract
New derivatives of S.sub.P - and R.sub.P -configures cyclic guanosine-3',5'-phosphorothioates and their physiologically and pharmaceutically acceptable salts according to the general formula ##STR1## are cell membrane permeable inhibitors (R.sub.P -isomers) and stimulators (S.sub.P -isomers) of cyclic GMP-dependent protein kinase which are resistant against phosphodiesterase degradation and suitable as ligands for affinity chromatography of cyclic nucleotide-dependent binding proteins.