The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 29, 1997
Filed:
Nov. 17, 1993
Applicant:
Inventors:
Monty Krieger, Needham, MA (US);
Keith A Joiner, New Haven, CT (US);
Assignees:
Massachusetts Institute of Technology, Cambridge, MA (US);
Yale University, New Haven, CT (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
514 21 ; 514-8 ; 514 12 ; 424851 ;
Abstract
Macrophage scavenger receptor protein or active fragments thereof bind specifically to the lipoteichoic acid residues on the Gram-positive bacterial cell wall. This protein or active fragments thereof can be used in a variety of methods including methods to specifically purify lipoteichoic acid, to preferentially label or detect lipoteichoic acid or lipoteichoic acid-containing compounds or cells, and to treat patients having Gram-positive bacterial infections such as septicemia and associated pathophysiological states such as septic shock.