The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 22, 1997
Filed:
May. 19, 1995
Applicant:
Inventor:
Sui-Ming Wong, Collegeville, PA (US);
Assignee:
Nano Systems L.L.C., Collegeville, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N / ; A61K / ;
U.S. Cl.
CPC ...
514 35 ; 424-129 ; 424490 ; 424493 ; 424499 ; 424-945 ;
Abstract
Dispersible particles consisting essentially of a crystalline drug substance having a surface modifier having the formula: ##STR1## wherein R is phenyl-(CH.sub.2).sub.10 CO or C.sub.12 H.sub.25 NHCO adsorbed on the surface thereof in an amount sufficient to maintain an effective average particle size of less than about 400 nm, methods for the preparation of such particles and dispersions containing the particles. Pharmaceutical compositions containing the particles exhibit unexpected bioavailability and are useful in methods of treating mammals.