The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 22, 1997
Filed:
Nov. 04, 1994
Applicant:
Inventors:
Paola Pedroni, Milan, IT;
Barbara Riboli, Cremona, IT;
Francesca De Ferra, Milan, IT;
Guido Grandi, Milan, IT;
Salvatore Toma, Milan, IT;
Beatrice Arico, Quercegrossa-Siena, IT;
Rino Rappuoli, Quercegrossa-Siena, IT;
Assignees:
Sclavo S.p.A., Siena, IT;
Eniricerche S.p.A., Milan, IT;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07K / ; C12N / ;
U.S. Cl.
CPC ...
4242531 ; 4041841 ; 4041851 ; 4042421 ; 435 691 ; 435 693 ; 435 711 ; 4352532 ; 43525233 ; 4353201 ; 530350 ;
Abstract
The cloning and sequencing of the gene which codes for a new pilinic subunit of Bordetella pertussis are described. The aminoacid sequence of the mature subunit, deduced from its necleotide sequence, is similar but not identical to that of the known pilins 2, 3 and 6. Polypeptides having the aminoacid sequence of the mature pilinic subunit or of regions thereof are particularly useful for the development of synthetic acellular vaccines against pertussis.