The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 15, 1997
Filed:
Oct. 13, 1994
Applicant:
Inventors:
David H Lynch, Bainbridge Island, WA (US);
Mark R Alderson, Bainbridge Island, WA (US);
Assignee:
Immunex Corporation, Seattle, WA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; C07K / ; C07K / ; C07K / ;
U.S. Cl.
CPC ...
435332 ; 5303882 ; 53038824 ; 53038823 ; 5303871 ; 53038875 ; 435334 ; 4353432 ; 4241441 ;
Abstract
The present invention provides a panel of monoclonal antibodies and binding proteins which specifically bind to human Fas antigen. Some of the antibodies and binding proteins are capable of stimulating T cell proliferation, inhibiting binding of anti-Fas CH-11 monoclonal antibody to cells expressing Fas antigen, blocking anti-Fas CH-11 monoclonal antibody-mediated lysis of cells, and blocking Fas ligand-mediated lysis of cells. The invention also provides for therapeutic compositions comprising the monoclonal antibodies.