The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 08, 1997

Filed:

Jun. 07, 1995
Applicant:
Inventors:

David Askin, Warren, NJ (US);

Paul Reider, Westfield, NJ (US);

Kai Rossen, Westfield, NJ (US);

Richard J Varsolona, Scotch Plains, NJ (US);

Ralph P Volante, Cranbury, NJ (US);

Kenneth M Wells, Somerville, NJ (US);

Assignee:

Merck & Co., Inc., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
544368 ; 544137 ; 544360 ; 544364 ; 544373 ; 544374 ; 544390 ; 546146 ; 546147 ; 548217 ; 549552 ;
Abstract

A process is disclosed for making a chiral compound of the formula ##STR1## comprising reacting an epoxide compound of the formula ##STR2## and an amide of the formula ##STR3## in the presence of a strong base at a low temperature.


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