The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 25, 1997
Filed:
Aug. 24, 1995
Applicant:
Inventors:
Radhakrishnan P Iyer, Shrewsbury, MA (US);
Theresa Devlin, Jamaica Plain, MA (US);
Ivan Habus, Shrewsbury, MA (US);
Dong Yu, Shrewsbury, MA (US);
Sudhir Agrawal, Shrewsbury, MA (US);
Assignee:
Hybridon, Inc., Worcester, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H / ; C07H / ; C07H / ; C07H / ; C07H / ;
U.S. Cl.
CPC ...
536 2533 ; 536 2534 ; 536 267 ; 536 2671 ; 536 268 ; 536 2762 ; 536 2781 ; 536 2851 ;
Abstract
The invention provides new methods for synthesizing oligonucleotides that allow for deprotection of the oligonucleotide under more mild conditions than existing methods. The invention further provides a nucleoside base protective group that is stable under oligonucleotide synthesis conditions, but which can be removed under more mild conditions than existing protective groups, as well as nucleoside synthons having such base protective groups.