The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 11, 1997
Filed:
Sep. 07, 1995
Applicant:
Inventors:
Assignee:
Warner-Lambert Company, Morris Plains, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
514414 ; 514415 ; 514421 ; 514406 ; 514407 ; 514359 ; 514255 ; 514 80 ; 544371 ; 544373 ; 544144 ; 544131 ; 544140 ; 544143 ; 5483611 ; 548491 ; 546201 ; 546199 ; 546194 ; 5462757 ; 5462774 ; 5462747 ; 546256 ; 546 22 ; 546 24 ; 424-91 ;
Abstract
The invention concerns tachykinin antagonists. The compounds are alcohols, amines and prodrugs of nonpeptides which have utility in treating disorders mediated by tachykinins. Such disorders are respiratory, inflammatory, gastrointestinal, ophthalmic, allergies, pain, vascular, diseases of the central nervous system, and migraine. Methods of preparing compounds and novel intermediates are also included. The compounds are expected to be especially useful in asthma, multiple sclerosis, rheumatoid arthritis, the management of pain, migraine, and antiemetic agents.