The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 11, 1997

Filed:

Jul. 26, 1995
Applicant:
Inventors:

Henri Wantier, Dour, BE;

Fabienne Mathieu, Nivelles, BE;

Marc Baudrihaye, Waterloo, BE;

Dominique Delacroix, Kraainem, BE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; B01J / ; B32B / ;
U.S. Cl.
CPC ...
424497 ; 424-125 ; 424-133 ; 424426 ; 424462 ; 424486 ; 42721336 ; 42840221 ; 514963 ;
Abstract

Microspheres which are a matrix of a biocompatible and biodegradable polymer which is soluble in an organic solvent which is immiscible in water, within which a water-soluble substance is uniformly distributed, and wherein the residual level of toxic solvent in the microspheres is lower than 1.5% by weight, progressively and continuously releases the substance over a period of at least 8 days when the microspheres are placed in an aqueous physiological environment, with a reduced or substantially absent first phase of accelerated release. A process for producing such microspheres is provided.


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