The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 04, 1997
Filed:
Aug. 25, 1994
Applicant:
Inventors:
Ulrich Stache, Hofheim, DE;
Hans-Georg Alpermann, K onigstein, DE;
Walter D urckheimer, Hattersheim, DE;
Manfred Bohn, Hofheim, DE;
Assignee:
Hoechst Aktiengesellschaft, Frankfurt am Main, DE;
Primary Examiner:
Int. Cl.
CPC ...
C07J / ; C07J / ; A61K / ;
U.S. Cl.
CPC ...
552601 ; 540107 ; 540108 ; 540111 ; 540112 ; 540113 ; 540114 ; 552588 ; 552595 ;
Abstract
Corticoid 17-alkyl carbonate 21-carboxylic and carbonic esters of the formula I ##STR1## are described in which A is CHOH and CHCl, CH.sub.2, C.dbd.O or 9(11) double bond; Y is H, F or Cl; Z is H, F or CH.sub.3 ; R(1) is aryl or hetaryl; n and m are zero or 1; R(2) is alkyl or --(CH.sub.2).sub.2 --OCH.sub.3 ; R(3) is H or methyl. They are obtained by reacting a compound of the formula II, ##STR2## in which R(5) is OH, with an activated carboxylic acid of the formula III,