The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 04, 1997
Filed:
Jul. 13, 1994
Applicant:
Inventors:
Assignee:
Nissin Shokuhin Kabushiki Kaisha, Osaka, JP;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P / ; C07K / ; A01K / ; C12N / ;
U.S. Cl.
CPC ...
435 696 ; 4351723 ; 43525233 ; 5303873 ; 53038835 ; 4241331 ; 4241601 ; 4241481 ;
Abstract
The present invention provides human monoclonal antibodies, derived from the murine mAb NM-01 (PCT/US92/07111), which are specifically reactive with HIV gp120 and have the capacity to neutralize the infection of H9 cells in culture by live HIV-1 strains MN and III.sub.B as shown by reverse transcriptase, p24 and syncytium formation assays. These antibodies were shown to be as or more effective than the parent murine antibody by the aforementioned criteria.