The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 1997
Filed:
Dec. 14, 1994
Applicant:
Inventors:
Hiroshi Kogen, Tokyo, JP;
Masaaki Kurabayashi, Tokyo, JP;
Teiichiro Koga, Tokyo, JP;
Toru Komai, Tokyo, JP;
Haruo Iwabuchi, Tokyo, JP;
Assignee:
Sankyo Company, Limited, Tokyo, JP;
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
514452 ; 544165 ; 548204 ; 548248 ; 549 71 ; 549 77 ; 549366 ; 549373 ; 549378 ; 549467 ; 549494 ; 560 73 ; 560107 ; 560252 ;
Abstract
Compounds of formula (I): ##STR1## (in which: R is hydrogen, methyl or hydroxy; X is alkyl, alkenyl, cycloalkyl, aryl, aralkyl, or a heterocyclic group; A is a single bond, or an alkylene, alkenylene, alkynylene or alkadienylene group; Y is hydrogen, aryl, cycloalkyl or a heterocyclic group) have the ability to inhibit the biosynthesis of cholesterol, and can thus be used for the treatment and prophylaxis of diseases relating to high blood cholesterol levels.