The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 04, 1997
Filed:
Apr. 01, 1994
Applicant:
Inventors:
Hiroo Matsumoto, Tokyo, JP;
Noriko Tanaka, Tokyo, JP;
Kiyoshi Nakayama, Tokyo, JP;
Haruko Chatani, Tokyo, JP;
Michio Iwahana, Tokyo, JP;
Assignee:
Daiichi Pharmaceutical Co., Ltd., Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07D / ;
U.S. Cl.
CPC ...
5142325 ; 5142332 ; 514258 ; 514221 ; 514368 ; 544117 ; 544278 ; 560 21 ; 560 43 ; 560 48 ; 560126 ; 560174 ; 560178 ; 564440 ; 540473 ; 540568 ;
Abstract
Thiazolopyrimidine derivatives represented by the formula ##STR1## and salts thereof are provided, which are characterized by a carboxamide residue substituted with R.sup.4 and R.sup.5. The derivatives and salts thereof exhibit antiangiogenic activity and are useful for treatment and cure of diseases, the development of which may be related to angiogenesis, including diabetic retinopathy, various chronic inflammation conditions, growth or metastasis of malignant solid tumors, rheumatism and psoriasis.