The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 04, 1997
Filed:
Jun. 28, 1994
Applicant:
Inventors:
Deborah DeFeo-Jones, Lansdale, PA (US);
Victor M Garsky, Blue Bell, PA (US);
Raymond E Jones, Lansdale, PA (US);
Allen I Oliff, Gwynedd Valley, PA (US);
Assignee:
Merck & Co., Inc., Rahway, NJ (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q / ; C12Q / ; A61K / ;
U.S. Cl.
CPC ...
435 23 ; 435 24 ; 435 18 ; 435-723 ; 435-71 ; 435-4 ; 4241851 ; 530322 ; 530300 ;
Abstract
Assays which comprise oligopeptides and which are useful for determining free PSA protease activity in vitro and in vivo are described. Such oligopeptides comprise amino acid sequences that are recognized and proteolytically cleaved by free prostrate specific antigen (PSA). Also described are assays useful in identifying inhibitors of free PSA.