The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 28, 1997
Filed:
Sep. 07, 1994
Applicant:
Inventor:
Jens J Brange, Klamponborg, DK;
Assignee:
Novo Nordisk A/S, Bagsvaerd, DK;
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61N / ; C07K / ;
U.S. Cl.
CPC ...
514-3 ; 424449 ; 530303 ; 604 20 ;
Abstract
Insulin analogues have been developed which are well suited for transdermal administration by iontophoresis. The insulin analogues have a negative charge at neutral pH and a reduced tendency to association. They are prepared by altering the human insulin molecule by substituting at least two of the amino acid residues of human insulin by Glu and/or Asp at selected positions in the molecule.