The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 21, 1997
Filed:
Mar. 15, 1995
Michael Meier, Frankfurt am Main, DE;
Heinz-Georg Kautz, Birstein, DE;
Hoechst Aktiengesellschaft, , DE;
Abstract
A process for the preparation of N-(2-sulfatoethyl)-piperazine in high purity, which comprises reacting N-(2-hydroxyethyl)piperazine in a mixture of highly--or relatively highly--concentrated sulfuric acid and oleum or chlorosulfonic acid at temperatures of from about 80.degree. to about 250.degree. C., transferring the resulting sulfonation mixture to a water-miscible aliphatic alcohol, isolating the N-(2-sulfatoethyl)piperazine sulfate formed, treating the N-(2-sulfatoethyl)piperazine sulfate, still moist with alcohol, at temperatures of from about 35.degree. to about 90.degree. C. with a basic compound in a mixture of a (C.sub.1 -C.sub.2)-alkanol and water, separating off the precipitated sulfate of the basic compound employed, and isolating the N-(2-sulfatoethyl)piperazine formed, by the addition of (C.sub.1 -C.sub.2)-alkanol.