The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 21, 1997
Filed:
Aug. 09, 1994
Teresa Kendrick, San Mateo, CA (US);
Bishwajit Nag, Fremont, CA (US);
Prabha V Mukku, Fremont, CA (US);
Somesh D Sharma, Los Altos, CA (US);
Anergen, Inc., Redwood City, CA (US);
Abstract
This invention provides a novel and rapid method for isolating MHC:antigen-restricted T cells. The method comprises the steps of (a) providing an isolated MHC:peptide complex wherein said complex is bound to a solid support; (b) contacting the complex with the biological sample containing T lymphocytes to form a MHC:peptide:T cell complex; (c) removing the MHC:peptide:T cell complex from the peripheral blood; and (d) separating the bound T lymphocytes from the MHC:peptide:T cell complex. The T-cells can be used to detect the presence, in a biological sample, of antigen presenting cells bearing a preselected MHC:antigen complex.