The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 21, 1997
Filed:
Sep. 03, 1993
John R Wetterau, II, Langhorne, PA (US);
Daru Y Sharp, Perrineville, NJ (US);
Richard E Gregg, Pennington, NJ (US);
Scott A Biller, Ewing, NJ (US);
John K Dickson, Mount Holly, NJ (US);
R Michael Lawrence, Yardley, PA (US);
John E Lawson, Wallingford, CT (US);
Henry M Holava, Meriden, CT (US);
Richard A Partyka, Neshanic, NJ (US);
Bristol-Myers Squibb Company, Princeton, NJ (US);
Abstract
Nucleic acid sequences, particularly DNA sequences, coding for all or part of the high molecular weight subunit of microsomal triglyceride transfer protein, expression vectors containing the DNA sequences, host cells containing the expression vectors, and methods utilizing these materials. The invention also concerns polypeptide molecules comprising all or part of the high molecular weight subunit of microsomal triglyceride transfer protein, and methods for producing these polypeptide molecules. The invention additionally concerns novel methods for preventing, stabilizing or causing regression of atherosclerosis and therapeutic agents having such activity. The invention concerns further novel methods for lowering serum liquid levels and therapeutic agents having such activity.