The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 07, 1997
Filed:
Dec. 16, 1993
James B Doherty, Montvale, NJ (US);
Conrad P Dorn, Plainfield, NJ (US);
Philippe L Durette, New Providence, NJ (US);
Paul E Finke, Milltown, NJ (US);
Malcolm Maccoss, Freehold, NJ (US);
Sander G Mills, Woodbridge, NJ (US);
Shrenik K Shah, Metuchen, NJ (US);
Soumya P Sahoo, Old Bridge, NJ (US);
Jeffrey J Hale, Westfield, NJ (US);
Thomas J Lanza, Edison, NJ (US);
William K Hagmann, Westfield, NJ (US);
Merck & Co., Inc., Rahway, NJ (US);
Abstract
New substituted azetidinones of the general Formula (I) which have been found to be potent elastase inhibitors and thereby useful anti-inflammatory and antidegenerative agents are described. ##STR1## wherein R.sub.4 is (a) ##STR2## or (b) ##STR3## where R.sub.x is carboxy C.sub.1-6 alkyl, benzyloxycarbonylC.sub.1-3 alkyl, or t-butoxycarbonylC.sub.1-3 alkyl, wherein