The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 07, 1997

Filed:

Jun. 17, 1994
Applicant:
Inventors:

Alan Townsend, Headington, GB;

Judy Bastin, Headington, GB;

Thierry Boon-Falleur, Brussels, BE;

Pierre van der Bruggen, Brussels, BE;

Pierre Coulie, Brussels, BE;

Thomas Gajewski, Brussels, BE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07K / ; C12N / ;
U.S. Cl.
CPC ...
424 9371 ; 4241851 ; 4242771 ; 435-724 ; 4352402 ; 530328 ; 530395 ; 530828 ;
Abstract

Tumor rejection antigens derived from tumor rejection precursor MAGE-3 have been identified. These 'TRAS' bind to the MHC-class I molecule HLA-A2, and the resulting complexes stimulate the production of cytolytic T cell clones which lyse the presenting cells. The peptides and complexes may be used diagnostically, therapeutically, and as immunogens for the production of antibodies, or as targets for the generation of cytolytic T cell clones.


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