The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 24, 1996
Filed:
Jul. 11, 1994
Applicant:
Inventors:
William H Kane, Durham, NC (US);
Thomas L Ortel, Durham, NC (US);
Assignee:
Duke University, Durham, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K / ; C07K / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
4352402 ; 435 696 ; 43525411 ; 4353201 ; 530381 ; 530383 ; 536 235 ;
Abstract
Chimeric blood coagulation proteins are disclosed. The proteins are (i) coagulation factor V in which at least one A3, C1 or C2 domain exon thereof is replaced with the homologous exon of coagulation factor VIII; or (ii) coagulation factor VIII in which at least one A3, C1 or C2 domain exon thereof is replaced with the homologous exon of coagulation factor V. The chimeric proteins are useful for diagnostic purposes in epitope mapping and for therapeutic purposes in facilitating blood coagulations in patients in need of such treatment.