The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 17, 1996
Filed:
Jun. 10, 1994
Elizabeth A Allegretto, La Jolla, CA (US);
J Wesley Pike, Encinitas, CA (US);
Ligand Pharmaceuticals Incorporated, San Diego, CA (US);
Abstract
The present invention features peptides derived from RXRX, and antibodies elicited by the peptides. These antibodies bind specifically to RXRX subtypes in its native, functional conformation. Methods are disclosed for detection of RXRX with the antibodies in immunological assays. In addition, this invention describes a hormone-binding immunoprecipitation assay which utilizes both the retinoid receptor subtype specific antibodies and retinoid receptor ligands to detect and measure RXR and RAR subtypes in a sample. A method is also disclosed for determining the profile of retinoid receptor subfamily members with the retinoid receptor ligands.