The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 10, 1996

Filed:

Oct. 06, 1993
Applicant:
Inventors:

Andreas Steinmeyer, Berlin, DE;

G unter Neef, Berlin, DE;

Gerald Kirsch, Berlin, DE;

Katica Schwarz, Berlin, DE;

Ruth Thieroff-Ekerdt, Berlin, DE;

Herbert Wiesinger, Berlin, DE;

Martin Haberey, Berlin, DE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C / ; A61K / ;
U.S. Cl.
CPC ...
514167 ; 552653 ;
Abstract

New 25-carboxylic acid derivatives of general formula I, ##STR1## R.sup.19 and R.sup.19a each mean a hydrogen atom or together form an exocyclic methylene group, R.sup.21 and R.sup.21a independently of one another mean a hydrogen atom, a chlorine or fluorine atom, an alkyl group with 1 to 4 carbon atoms, together a methylene group, together with quaternary carbon atom 20 mean a 3-7 membered, saturated or unsaturated carboxylic ring, Y preferably means a derivatized carboxyl radical, and the other substituents have the meanings indicated in the description as well as process for their production, are described. The new compounds have vitamin D activity as well as proliferation-inhibiting and cell-differentiating effects and are suitable for the production of pharmaceutical agents.


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