The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 10, 1996

Filed:

Nov. 14, 1994
Applicant:
Inventors:

Axel Kretschmer, Begisch Gladbach, DE;

Horst-Peter Antonicek, Begisch Gladbach, DE;

Jorg Baumgarten, Wuppertal, DE;

Antonius Loebberding, Wuppertal, DE;

Burkhard Mielke, Leverkusen, DE;

Wolfgang Springer, Wuppertal, DE;

Udo Stropp, Haan, DE;

Mark-Michael Struck, Bern, CH;

Lothar Biesert, Frankfurt, DE;

Helga Rubsamen-Waigmann, Bad Soden, DE;

Hary Suhartono, Frankfurt, DE;

Thomas-Peter Hausner, Cologne, DE;

Assignee:

Bayer Aktiengesellschaft, Leverkusen, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12H / ; C12H / ;
U.S. Cl.
CPC ...
4352402 ; 435-6 ; 435 911 ; 435 9121 ; 435 9133 ; 4351723 ; 4353201 ; 536 231 ; 536 2372 ; 536 245 ;
Abstract

The present invention relates to the targeted blocking of the genetic information of the viral messenger ribonucleic acid (mRNA) for virus replication (e.g. of HIV) in transfected, haematopoietic cells with particularly suitable expression systems, which express a complementary 'antisense RNA'.


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