The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 03, 1996
Filed:
Jul. 30, 1993
Chil-Yong Kang, London, CA;
Lizhong Luo, London, CA;
Korea Green Cross Corporation, Kyongki-Do, KR;
Abstract
An unprocessed human immunodeficiency virus 2 (HIV-2) gag precursor protein, containing a deficient protease, assembles into virus-like particles by budding through the cytoplasmic domain of baculovirus-infected cells. Chimeric constructs were generated by coupling the truncated HIV-2 gag gene to the neutralizing domain (V3) or the neutralizing and CD4 binding domains (V3+CD4B) of gp120 env gene sequences obtained from HIV-1 or HIV-2. Virus-like particles were formed by chimeric gene products when the env gene sequences were linked to the 3' terminus of the gag gene. The gag-env chimeric proteins displayed immunoreactivity towards anti-gp120 rabbit antisera.