The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 12, 1996
Filed:
Jan. 06, 1995
Applicant:
Inventors:
Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N / ; A61K / ; C07G / ; C12P / ;
U.S. Cl.
CPC ...
514 54 ; 435101 ; 536 186 ;
Abstract
The invention stabilizes single helix conformation (1.fwdarw.3)-.beta.-D-glucans by intramolecular crosslinking and provides (1.fwdarw.3)-.beta.-D-glucans showing stable biological activities. Thus, intramolecularly crosslinked (1.fwdarw.3)-.beta.-D-glucans having a stable single helix conformation are produced by introducing a functional group into hydroxyl groups of (1.fwdarw.3)-.beta.-D-glucans, then causing the thus-obtained functional glucans to take a single helix conformation, and subjecting these, either as such or after binding them to a receptor therefor, to intramolecular crosslinking between the functional groups introduced, if necessary followed by releasing the receptor therefrom.