The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 12, 1996
Filed:
Oct. 03, 1994
Applicant:
Inventors:
Jacob Victor, Passaic, NJ (US);
Lisa M Pieti, Norwalk, CT (US);
Assignee:
Lifecodes Corp., Stamford, CT (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q / ;
U.S. Cl.
CPC ...
435-6 ; 435-71 ; 435-792 ; 435973 ; 435975 ; 436501 ; 436506 ; 436508 ; 436518 ; 436531 ; 436808 ; 436809 ;
Abstract
The subject invention pertains to a method of binding proteins and double-stranded DNA to the same membrane matrix. The DNA bound to the membrane matrix remains in double-stranded form. The subject invention further concerns an assay procedure for detecting antibodies, such as autoimmune antibodies, in a biological sample that are immunoreactive with the proteins and double-stranded DNA attached to a membrane matrix. The subject invention provides a single assay system that allows for the determination of antinuclear antibody specificities which can be used to aid in the diagnosis and monitoring of autoimmune diseases.