The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 12, 1996
Filed:
Aug. 04, 1995
Applicant:
Inventor:
Bernard C Sherman, Willowdale, CA;
Assignee:
Apotex USA Inc., Buffalo Grove, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
424464 ; 424465 ; 514960 ; 514970 ;
Abstract
There is disclosed a stable pharmaceutical solid composition comprising enalapril as the sodium salt, which is made by the steps of: i) mixing enalapril maleate with a carrier, an alkaline sodium compound, and water ii) drying the wet mass, and; iii) further processing the resultant dried mass into tablets. When the water is added in the aforesaid process, an acid-base reaction occurs which converts the enalapril maleate into the more stable enalapril sodium salt.