The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 05, 1996
Filed:
Sep. 06, 1991
Applicant:
Inventors:
James R Dasch, Palo Alto, CA (US);
Doran R Pace, III, San Francisco, CA (US);
Wendy O Waegell, Mountain View, CA (US);
Assignee:
Celtrix Pharmaceuticals, Inc., Santa Clara, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; C07K / ; C12P / ; A61K / ;
U.S. Cl.
CPC ...
43524027 ; 4241451 ; 4241581 ; 4241981 ; 435 7021 ; 4351722 ; 53038823 ; 53038824 ; 5303892 ; 530399 ;
Abstract
Monoclonal antibodies have been produced which bind to Transforming Growth Factors .beta.1 (TGF-.beta.1) and .beta.2 (TGF-.beta.2). The monoclonal antibody produced by the hybridoma designated 1D11.16 deposited as A.T.C.C. Accession No. HB 9849 binds to both TGF-.beta.1 and TGF-.beta.2. The antibodies are produced by immunizing with TGF-.beta.2 and may be of any isotype. The antibodies may be of any mammalian origin such as murine or human origin. Diagnostic and therapeutic applications utilizing the monoclonal antibodies are also disclosed.