The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 22, 1996
Filed:
Sep. 21, 1994
Darren Magda, Cupertino, CA (US);
Jonathan L Sessler, Austin, TX (US);
Brent Iverson, Austin, TX (US);
Petra L Jansen, Austin, TX (US);
Meredith Wright, San Jose, CA (US);
Tarak D Mody, Sunnyvale, CA (US);
Gregory W Hemmi, Sunnyvale, CA (US);
University of Texas, Austin, TX (US);
Pharmacyclics, Inc., Sunnyvale, CA (US);
Abstract
A texaphyrin having substituents containing ethoxy groups, methods for using texaphyrins in photodynamic therapy, and cleavage of a polymer of deoxyribonucleic acid are disclosed. The in vivo treatment of tumors and atheroma is demonstrated using Lu(III)texaphyrin complexes. A preferred method of use is the site-specific cleavage of a polymer of deoxyribonucleic acid and a preferred texaphyrin is a derivatized texaphyrin having binding specificity, in particular, a texaphyrin covalently coupled to a site-directing molecule, preferably an oligonucleotide.