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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 5565552 B1

PDFFull Text
Date of Patent:
Oct. 15, 1996

Filed:

Jun. 07, 1995

Method of expanded porphyrin-oligonucleotide conjugate synthesis

Applicant:
Inventors:

Darren Magda, Cupertino, CA (US);

Jonathan L Sessler, Austin, TX (US);

Brent L Iverson, Austin, TX (US);

Petra I Sansom, Austin, TX (US);

Shaun P Crofts, Campbell, CA (US);

Assignees:

Pharmacyclics, Inc., Sunnyvale, CA (US);

Board of Regents, Univ. of Texas Sys., Austin, TX (US);

Attorney:

Larson; Jacqueline S.

Primary Examiner:

Richard L Raymond

Int. Cl.
CPC ...
C07D / ;
U.S. Cl.
CPC ...
534 11 ; 530345 ; 5303913 ; 5303915 ; 530405 ; 534 13 ; 534 15 ; 534 16 ; 536 173 ; 536 174 ; 540149 ; 540465 ; 540472 ;
Abstract

The invention is directed to a method of incorporating expanded porphyrins, and particularly of incorporating a sapphyrin or a texaphyrin, before, during, or after chemical synthesis of an oligomer to form an expanded porphyrin-oligonucleotide conjugate, and particularly a sapphyrin- or texaphyrin-oligonucleotide conjugate. This method includes reacting derivatized nucleotides and a sapphyrin or a texaphyrin in a desired order in an automated or manual DNA synthesizer having a solid support to form a sapphyrin- or a texaphyrin-oligonucleotide conjugate.

Find Patent Forward Citations

Magda, Darren. (1996). Method of expanded porphyrin-oligonucleotide conjugate synthesis (U.S. Patent No. 5565552). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5565552

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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