The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 15, 1996
Filed:
Nov. 10, 1992
Applicant:
Inventors:
Victor E Marquez, Gaithersburg, MD (US);
John S Driscoll, Rockville, MD (US);
Christopher K-H Tseng, Burtonsville, MD (US);
James A Kelley, Silver Spring, MD (US);
David G Johns, Bethesda, MD (US);
Hiroaki Mitsuya, Rockville, MD (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
514 45 ; 514 46 ; 514885 ; 536 267 ; 536 271 ; 536 2713 ; 536 2714 ; 536 276 ; 536 278 ; 536 2781 ;
Abstract
Methods of treating a human infected with human immunodeficiency virus (HIV), such as a human with AIDS, with the purina nucleotides 2',3'-dideoxy-2'-beta-fluoroadenosine (FddA) and 2',3'-dideoxy-2'-beta-fluoroinosine (FddI) are disclosed. These nucleotides are stable in an acid environment and thus can be used for oral administration. Methods of inhibiting human immunodeficiency virus replication in a human T cell using these purina nucleotides are also disclosed.