The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 08, 1996

Filed:

Apr. 12, 1995
Applicant:
Inventors:

Richard B Silverman, Morton Grove, IL (US);

Ryszard Andruszkiewicz, Sopot, PL;

Po-Wai Yuen, Ann Arbor, MI (US);

Denis M Sobieray, Holland, MI (US);

Lloyd C Franklin, Hamilton, MI (US);

Mark A Schwindt, Holland, MI (US);

Assignees:

Northwestern University, Evanston, IL (US);

Warner-Lambert Company, Ann Arbor, MI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
514561 ; 514567 ; 514568 ; 562443 ; 562507 ; 562553 ; 562571 ;
Abstract

A compound of the formula ##STR1## wherein R.sub.1 is a straight or branched alkyl group having from 1 to 6 carbon atoms, phenyl, or cycloalkyl having from 3 to 6 carbon atoms; R.sub.2 is hydrogen or methyl; and R.sub.3 is hydrogen, methyl or carboxyl; which is useful in the treatment of seizure disorders. Processes are disclosed for the preparation of the compound. Intermediates prepared during the synthesis of the compound are also disclosed.


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