The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 08, 1996

Filed:

Oct. 14, 1994
Applicant:
Inventors:

Tasuku Honjo, Kyoto, JP;

Michio Shirozu, Kyoto, JP;

Hideaki Tada, Osaka, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C07K / ;
U.S. Cl.
CPC ...
435 691 ; 4351723 ; 4352401 ; 4352523 ; 4353201 ; 536 231 ; 536 235 ; 935 11 ; 935 22 ; 935 52 ; 935 66 ;
Abstract

The Stromal Derived Factor-1.alpha. (SDF-1.alpha.) and Stromal Derived Factor-1.beta. (SDF-1.beta.) polypeptides of the present invention are produced and secreted in pro-B cells, so they may be used for diseases relating to undergrown or abnormal proliferation of hematopoietic cells, neuronal enhancement or depression, immunological enhancement and depression, for example, inflammatory diseases (rheumatoid arthritis, ulcerative colitis etc.), hematopoietic stemcytopenia after bone marrow transplantation, leukocytopenia, thrombocytopenia, B lymphopenia and T lymphopenia after chemotherapy, anemia, infectious diseases, cancer, leukocytosis, AIDS, neurodegenerative diseases (Alzheimer, multiple sclerosis etc.), prevention or treatment of neuronal injury, prevention or treatment of disorder of bone metabolism (osteoporosis etc.) or tissue repair. The DNAs of the present invention may be utilized as important and essential templates in preparing the polypeptides of the present invention which are expected to possess various uses or for diagnosis of and in the treatment of gene diseases.


Find Patent Forward Citations

Honjo, Tasuku. (1996). Human stromal derived factor 1.alpha. and 1.beta., and dnas encoding the (U.S. Patent No. 5563048). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5563048

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