The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 24, 1996

Filed:

Dec. 05, 1994
Applicant:
Inventors:

Lodewyk J Mienie, Potchefstroom, ZA;

Ronald A Van Steenderen, Pretoria, ZA;

Elardus Erasmus, Fochville, ZA;

Julius H Ueckermann, Pretoria, ZA;

Wouter J De Wet, Potchefstroom, ZA;

Henning J Els, Potchefstroom, ZA;

Assignees:

CSIR, Pretoria, ZA;

Potchefstroom University for Christian Higher Education, Potchefstroom, ZA;

Lekratek Instrumentation, Potchefstroom, ZA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N / ;
U.S. Cl.
CPC ...
436 63 ; 436145 ; 422 80 ; 422 83 ;
Abstract

A method and apparatus for the preliminary detection of abnormal levels of metabolites in the urine of a human or mammal. The method includes the steps of determining the amount of creatinine in the urine of the human or animal, measuring the total metabolites content in the urine, using the amount of creatinine in the urine as an internal standard to compensate for variations in the urine concentration, and comparing the total metabolites content in the urine with a reference value which corresponds to the expected total metabolites content in the urine of a person or animal who does not suffer from a metabolic disorder. The apparatus (10) includes an ultraviolet oxidation unit (16) for oxidising total metabolites in a urine sample to carbon dioxide, an organic carbon stripper (18) for stripping carbon dioxide gas from the oxidised sample, and a carbon dioxide detector (69) for measuring the amount of carbon dioxide produced from the sample.


Find Patent Forward Citations

Loading…