The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 17, 1996

Filed:

Jan. 05, 1995
Applicant:
Inventors:

Koichi Fujimoto, Tokyo, JP;

Naoki Tanaka, Tokyo, JP;

Fumitoshi Asai, Tokyo, JP;

Tomiyoshi Ito, Tokyo, JP;

Hiroyuki Koike, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C / ; C07C / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
514315 ; 5142378 ; 5142382 ; 5142388 ; 5142392 ; 5142395 ; 514331 ; 514427 ; 514428 ; 514415 ; 514650 ; 514651 ; 544386 ; 544391 ; 544162 ; 544170 ; 546192 ; 546201 ; 546225 ; 548570 ; 548578 ; 560123 ; 560127 ; 560129 ; 562444 ; 562471 ; 564337 ; 564347 ; 564348 ; 564349 ; 564353 ; 564362 ;
Abstract

Compounds of formula (I): ##STR1## [wherein: R.sup.1 is aryl; R.sup.2 is hydrogen, alkyl, alkoxy, halogen or cyano; R.sup.3 is a group of formula --B--NR.sup.4 R.sup.5, where R.sup.4 and R.sup.5 are independently hydrogen, alkyl or substituted alkyl or R.sup.4 and R.sup.5, together with the nitrogen to which they are attached, form a heterocycle, and B is alkylene or a group of formula --CH.sub.2 CH(OR.sup.6)CH.sub.2 --, where R.sup.6 is hydrogen, alkanoyl, substituted alkanoyl or arylcarbonyl, or a group of formula --D--R.sup.7, where D is a single bond or alkylene and R.sup.7 is a heterocycle; and A is alkylene; and pharmaceutically acceptable salts and esters thereof] are useful for the treatment and prevention of circulatory diseases and psychosis.


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