The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 17, 1996
Filed:
Dec. 02, 1994
Applicant:
Inventors:
Robert J Suhadolnik, Roslyn, PA (US);
Wolfgang Pfleiderer, Konstanz, DE;
Assignee:
Temple University - Of The Commonwealth System of Higher Education, Philadelphia, PA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07H / ;
U.S. Cl.
CPC ...
514 44 ; 514889 ; 504127 ; 504129 ; 504139 ; 504153 ; 504197 ; 536 252 ; 536 256 ;
Abstract
Optically active compounds of the formula ##STR1## wherein n is 1 or 2 and m is 0, 1, 2 or 3 have antiviral activity. Compounds of the formula wherein at least one of the internecleotide phosphorothioate linkages is of the Sp configuration possess increased antiviral activity and/or metabolic stability.