The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 10, 1996
Filed:
Dec. 01, 1993
Applicant:
Inventors:
Melvyn Hollis, Alderley Edge, GB;
David Pioli, Alderley Edge, GB;
Dario Valenzuela, Somerville, MA (US);
Assignees:
Imperial Chemical Industries, PLC, London, GB;
President and Fellows of Harvard College, Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ;
U.S. Cl.
CPC ...
435 691 ; 4351721 ; 4351723 ; 4352401 ; 4352523 ; 4352542 ; 43525421 ; 4353201 ; 536 231 ; 536 241 ; 935 33 ;
Abstract
The present invention relates to the regulation of gene expression which entails providing a pair of unlike proteins, with unlike DNA binding domains, which will associate to form a heterodimer and bind to appropriate asymmetric DNA binding sites and hence depress or increase expression of adjacent genes.