The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 03, 1996
Filed:
Nov. 03, 1994
Applicant:
Inventors:
Lawrence J MacPherson, Hampton, NJ (US);
David T Parker, Livingston, NJ (US);
Assignee:
Ciba-Geigy Corporation, Tarrytown, NY (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ; A61K / ;
U.S. Cl.
CPC ...
514357 ; 544 581 ; 544168 ; 544130 ; 544131 ; 544133 ; 540524 ; 540531 ; 514604 ; 546175 ; 546194 ; 546247 ; 546209 ; 546265 ; 5462834 ; 5462821 ; 546333 ; 546337 ; 5462804 ; 5462844 ; 5462817 ; 5462751 ; 548205 ; 5483351 ; 5483381 ; 549 13 ; 549 65 ; 549426 ; 564 84 ; 564 90 ; 564 92 ; 564 94 ; 5142378 ; 514311 ; 514331 ; 514332 ; 514341 ; 514365 ; 514396 ; 514406 ; 514432 ; 514445 ; 514451 ; 514602 ;
Abstract
The invention relates to the compounds of formula I ##STR1## pharmaceutically acceptable prodrug derivatives and pharmaceutically acceptable salts thereof; methods for preparation thereof; pharmaceutical compositions comprising said compounds; and a method of inhibiting matrix-degrading metalloproteinase and of treating matrix-degrading metalloproteinase dependent conditions in mammals using such compounds.