The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 03, 1996
Filed:
Jul. 31, 1995
Applicant:
Inventors:
Vida Gorys, Dollard des Ormeaux, CA;
Francedilla.ois Soucy, Lachenaie, CA;
Christiane Yoakim, Laval, CA;
Pierre L Beaulieu, Montr eal, CA;
Assignee:
Bio-Mega/Boehringer Ingelheim Research, Inc., Laval, CA;
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
514269 ; 514314 ; 514343 ; 514423 ; 514319 ; 546169 ; 5462784 ; 546256 ; 5462791 ; 5462697 ; 548537 ;
Abstract
Disclosed herein are compounds of formula 1 ##STR1## wherein X is a terminal group, for example, an aryloxycarbonyl or an alkanoyl; B is absent or an amino acid residue, for example, Val or Asn; R.sup.1 is alkyl; and Y is a ring substituent, for example, benzyl, benzyloxy, phenylthio or 2-pyridinylthio. The compounds inhibit the activity of human immunodeficiency virus (HIV) protease and interfere with HIV induced cytopathogenic effects in human cells. These properties render the compounds useful for combating HIV infections.