The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 03, 1996

Filed:

Feb. 23, 1994
Applicant:
Inventors:

Kam M Hui, Kent Ridge, SG;

Jeffrey L Bidwell, Bristol, GB;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q / ; C12Q / ; C21P / ;
U.S. Cl.
CPC ...
435-6 ; 435 15 ; 435 912 ; 4351721 ; 435810 ; 935 17 ; 935 77 ; 935 78 ;
Abstract

A method of human HLA-DR and/or Dw allotype matching comprises: (i) effecting polymerase chain reaction (PCR) amplification of a HLA-DRB gene exon 2 nucleotide sequence of a first sample of DNA; (ii) separating according to size the DNA fragments resulting from the said amplification; (iii) determining the length polymorphism of the thus separated DNA fragments; and (iv) comparing the thus-determined length polymorphism with the length polymorphism of DNA fragments resulting from PCR amplification of the said HLA-DRB gene exon 2 nucleotide sequence of a second sample of DNA.


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