The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 20, 1996

Filed:

Jan. 04, 1994
Applicant:
Inventor:

Eliezer Rapaport, Belmont, MA (US);

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07H / ;
U.S. Cl.
CPC ...
514 47 ; 514 46 ;
Abstract

The administration of adenine nucleotides or adenosine and inorganic phosphate to a human patient results in the generation of elevated liver, other organs and red blood cell adenosine 5'-triphosphate (ATP) pools as well as increased levels of ATP in the extracellular blood plasma compartment of the blood. The present invention deals with the utilization of the elevated extracellular levels of ATP for achieving the well-established stimulation of insulin secretion following the interactions of extracellular ATP pools with pancreatic .beta. cell purine receptors. The invention is therefore concerned with the treatment of patients suffering from non-insulin-dependent diabetes mellitus (NIDDM or Type-II diabetes) and their chronic clinical complications which are the result of continuous hyperglycemia, by the administration of these physiological agents.


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