The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 13, 1996
Filed:
Jan. 18, 1994
Applicant:
Inventors:
Yukio Sato, Tokyo, JP;
Atsushi Sato, Tokyo, JP;
Tatsuro Sumikawa, Tokyo, JP;
Tazuo Uemura, Tokyo, JP;
Assignee:
Daiichi Pharmaceutical Co., Ltd., Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ;
U.S. Cl.
CPC ...
544101 ;
Abstract
A process for selectively producing an (S)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3 -dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid hemihydrate or monohydrate as depicted below, which comprises controlling the water content of an aqueous solvent in which an (S)-9-fluoro-3-methyl-10-(4-methyl-1-piperazin -yl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid is dissolved during a crystallization. ##STR1##