The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 06, 1996
Filed:
Aug. 13, 1993
Applicant:
Inventors:
Alan McClelland, Gaithersburg, MD (US);
Susan C Stevenson, Federick, MD (US);
Assignee:
Genetic Therapy, Inc., Gaithersburg, MD (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C12N / ; A61K / ;
U.S. Cl.
CPC ...
4353201 ; 424 931 ; 424 932 ; 536 234 ; 536 2372 ; 935 22 ; 935 32 ; 935 57 ;
Abstract
An adenovirus wherein the adenovirus fiber protein includes a ligand which is specific for a receptor located on a desired cell type. The adenovirus may have at least a portion of the adenovirus fiber protein removed and replaced with a ligand which is specific for a receptor located on a desired cell type, or the adenovirus may include a fusion protein of the adenovirus fiber protein and the ligand. Such an adenovirus may also include a gene(s) encoding a therapeutic agent(s) and may be 'targeted' in order to deliver such gene(s) to a desired cell type.