The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 30, 1996

Filed:

Jun. 27, 1994
Applicant:
Inventors:

Volker Breu, Schliengen, DE;

Kaspar Burri, Binningen, CH;

Jean-Marie Cassal, Mulhouse, FR;

Martine Clozel, Saint-Louis, FR;

Georges Hirth, Huningue, FR;

Bernd-Michael L offler, Oberrimsingen, DE;

Marcel M uller, Frenkendorf, CH;

Werner Neidhart, Bartenheim, FR;

Henri Ramuz, Birsfelden, CH;

Assignee:

Hoffmann-La Roche Inc., Nutley, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
514256 ; 514269 ; 514272 ; 514273 ; 514274 ; 514275 ; 514212 ; 5142278 ; 5142322 ; 5142358 ; 5142365 ; 514252 ; 514262 ; 514265 ; 514266 ; 540601 ; 544295 ; 544296 ; 544 582 ; 544 586 ; 544 60 ; 544 82 ; 544122 ; 544123 ;
Abstract

A compound of the formula ##STR1## wherein R.sup.1 to R, R.sup.a, R.sup.b X, Y, Z, m and n have the significance given in the description, can be used as medicaments, especially for the treatment and prophylaxix of conditions which are associated with endothelin activities.


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