The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 18, 1996

Filed:

Dec. 03, 1993
Applicant:
Inventors:

Choong S Kim, Seoul, KR;

Jin W Kim, Seongnam, KR;

Jae M Lee, Seoul, KR;

Il H Cho, Suwon, KR;

Yong S Youn, Suwon, KR;

Young J Shin, Seoul, KR;

Ki H Lee, Suwon, KR;

Je H Kim, Suwon, KR;

Yong H Jung, Kyonggi-do, KR;

Seung H An, Seoul, KR;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; C07D / ; A61K / ;
U.S. Cl.
CPC ...
546156 ; 546112 ; 546123 ; 548452 ;
Abstract

Pyridone carboxylic acid compounds or physiologically hydrolyzable esters thereof are provided which are represented by the formula: ##STR1## wherein R.sub.1 is a lower alkyl, a halogen-substituted lower alkyl, a lower alkenyl, a cycloalkyl, or a substituted- or unsubstituted-phenyl group; R.sub.2 is a hydrogen atom, or a lower alkyl or an amino group; A is a nitrogen atom or the group C-X wherein X is a hydrogen or a halogen atom, or an alkoxy group; and Z is a group having the formula: ##STR2## wherein n is 1 or 2; R.sub.3 and R.sub.4 each represent a hydrogen atom or a lower alkyl group, with proviso that, if n is 2, one of R.sub.3 and R.sub.4 is a hydrogen atom; R.sub.5 and R.sub.6 each represent a hydrogen atom, or a hydroxy, a lower alkoxy or an amino group which is unsubstituted or substituted by a lower alkyl group, with proviso that one of R.sub.5 and R.sub.6 is a hydrogen atom; and R.sub.7 is a hydrogen atom or a lower alkyl group. The compounds of the present invention show potent and broad spectrum of antibacterial activities.


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