The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 18, 1996

Filed:

Jun. 07, 1995
Applicant:
Inventors:

Theresa M Williams, Harleysville, PA (US);

Terrence M Ciccarone, East Greenville, PA (US);

Walfred S Saari, Lansdale, PA (US);

John S Wai, Harleysville, PA (US);

William J Greenlee, Teaneck, NJ (US);

Suresh K Balani, Hatfield, PA (US);

Mark E Goldman, San Diego, CA (US);

Anthony D Theoharides, deceased, late of Lansdale, PA (US);

Jacob M Hoffman, Jr, Landsale, PA (US);

William C Lumma, Jr, Pennsburg, PA (US);

Joel R Huff, Gwynedd Valley, PA (US);

Clarence S Rooney, Worcester, PA (US);

Philip E Sanderson, Philadelphia, PA (US);

Assignee:

Merck & Co., Inc., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ; A61K / ;
U.S. Cl.
CPC ...
514419 ; 548492 ;
Abstract

Novel indole compounds inhibit HIV reverse transcriptase, and are useful in the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, anti-infectives, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.


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