The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 11, 1996
Filed:
May. 24, 1993
Saresh C Srivastava, Waltham, MA (US);
Syed K Raza, Waltham, MA (US);
Chemgenes Corporation, Waltham, MA (US);
Abstract
This invention is directed to processes for producing high purity N-protected-2'-O-methyl-5'-dimethoxytrityl-3' ribonucleoside methoxy, N,N-diisopropyl phosphoramidites (group 1), and N-protected-2'-O-methyl-5'-dimethoxytrityl-3'-ribonucleoside ethoxy, N,N-diisopropyl phosphoramidites (group 2). This invention is further directed to the process for producing high purity 2'-O-methyl-5'-dimethoxytrityl-inosine (structure IX; group 3), and 2'-O-methyl-5'-dimethoxytrityl-inosine-3'-cyanoethyl, N,N-diisopropyl phosphoramidite (structure Xa; group 3). This invention is also directed to the process for producing high purity N-protected-3'-O-methyl-5'-dimethoxytrityl ribonucleosides (group 6), and N-protected-3'-O-methyl-5'-dimethoxytrityl-2'-ribonucleoside cyanoethyl, N,N-diisopropyl phosporamidites (group 7).