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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 5523460 B1

PDFFull Text
Date of Patent:
Jun. 04, 1996

Filed:

Mar. 28, 1994

4-fluorobiphenyl derivatives

Applicant:
Inventors:

Masakatsu Matsumoto, Sagamihara, JP;

Nobuko Watanabe, Tokyo, JP;

Eiko Mori, Tokyo, JP;

Miwa Ishihara, Tokyo, JP;

Tetsuaki Yamaura, Tokyo, JP;

Misao Aoyama, Tokyo, JP;

Hiroshi Ikawa, Tokyo, JP;

Hisako Kobayashi, Tokyo, JP;

Assignee:

Fujirebio Inc., Tokyo, JP;

Attorney:

Oblon, Spivak, McClelland, Maier & Neustadt

Primary Examiner:

Paul J Killos

Int. Cl.
CPC ...
C07C / ; A01N / ;
U.S. Cl.
CPC ...
560 60 ; 560 53 ; 562463 ; 562470 ; 549292 ;
Abstract

A 4-fluorobiphenyl derivative of formula (I), which is useful as a cholesterol lowering agent or a lipid lowering agent because of its strong inhibitory effect on HMG-CoA reductase), and which is also useful as an intermediate for producing the above-mentioned cholesterol lowering agent or lipid lowering agent: ##STR1## wherein A is a .omega.-oxycarbonyldihydroxybutyl group, a tetrahydropyranyl group, a .omega.-oxycarbonyl-3-oxobutyl group, a formyl group, or a cyano group; R.sup.1 is a halogen atom, an alkyl group, or a group represented by R.sup.5 O--, wherein R.sup.5 is a hydrogen atom, or an alkyl group; R.sup.2 is a hydrogen atom, an alkyl group; R.sup.3 is a hydrogen atom, or an alkyl group; R.sup.5 and R.sup.2 may form a five-membered ring or a six-membered ring in combination with the oxygen atoms to which R.sup.5 and R.sup.2 are respectively bonded, and R.sup.5 and R.sup.3 may form a five-membered ring or a six-membered ring in combination with the oxygen atom to which R.sup.5 is bonded.

Find Patent Forward Citations

Matsumoto, Masakatsu. (1996). 4-fluorobiphenyl derivatives (U.S. Patent No. 5523460). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5523460

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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